Endocrine Abstracts

Introduction: The presentation of new onset hyperandrogenism is extremely rare in postmenopausal women. In premenopausal women, the most common cause of androgen excess is polycystic ovary syndrome. In contrast, when hyperandrogenism develops in postmenopausal women, it is usually associated with other causes, such as ovarian hyperthecosis or an androgen secreting tumor. We describe 5 patients with hyperandrogenism (Table 1). Total Testosterone 0.06–0.86 ng/ml, free testo...

Introduction: Central diabetes insipidus (DI) is a common complication after pituitary surgery, but is transient in the majority of patients. The aim of our study is to determine the incidence and course of DI in the postoperative period and to characterize the factors associated with this disease.Methods: We performed a retrospective study of 44 patients (50% females) with a mean age of 54 years (24–83), treated with transsphenoidal (TSS) or transf...

Introduction: Ectopic Cushing’s syndrome (ECS) is due to ACTH secretion of no pituitary neuroendocrine tumors and represents around 5–10% of all cases of ACTH dependent Cushing’s syndromes.Methods: Six cases of ECS diagnosticated from 2008 to 2017 were studied. Patients’ age ranges from 36 to 69 years (mean 53), four females and two males. Three had pancreatic tumors, two small cell lung carcinomas and one pheocromocytoma. At diagnosi...

IntroductionMalignant insulinoma is a rare pancreatic neuroendocrine tumor that accounts for only 10% of all cases of insulinoma. The clinical picture is characterized by the presence of severe hyperinsulinemic hypoglycaemic syndrome in a patient with pancreatic tumor with locoregional and/or distant metastases. Therapeutic management is challenging due to the need to control both hypoglycemic syndrome and tumor growth. Curative surgery is rarely applica...